Frontiers in Bioscience-Landmark

Frontiers in Bioscience-Landmark (Landmark) is an international peer-reviewed open access journal of biological science. The journal integrates the art of science publication with a diverse array of information, tools, and techniques. Data and information that are useful to investigators in any discipline in biology and medicine including biochemistry, molecular biology, botany, agronomy, microbiology, parasitology, virology, immunology, biotechnology, marine biology, clinical and basic medicine, biomedical engineering, genetics, epidemiology and preventive medicine, ecology, entomology, bioinformatics will be published following peer review. This will include reviews and research articles in basic science and clinical science, as well as technical notes and protocols.

Open Access: Free for readers, with article processing charges (APC) paid by authors or their institutions.

High Visibility: Indexed by the Science Citation Index Expanded (Web of Science), MEDLINE (PubMed), Scopus, Current Contents - Life Sciences, Zoological Record, BIOSIS Previews, Index Medicus, Research Alert, Current Web Content, Chemical Abstracts and other databases.

Peer Review: Manuscripts are peer-reviewed and a first decision is provided to authors approximately 30 days after submission. Time from submission to acceptance is approximately 50-60 days.

For more information about Landmark.


Current Articles
Open Access
Editorial

Clinical significance of inflammatory markers of bacterial infection in critically ill patients with COVID-19 after treatment with anti-inflammatory and immunomodulatory drugs: a complex new scenario

Daniele Roberto Giacobbe, Lorenzo Ball, Laura Magnasco, Chiara Dentone, Denise Battaglini, Chiara Robba, Paolo Pelosi, Matteo Bassetti
Frontiers in Bioscience-Landmark Volume 26 Issue 9, pp.405-408
Managing Editor: Alessandro Poggi
DOI: 10.52586/4954 Published: 30 September 2021
Open Access
Editorial

Health threat caused by fungi of medical interest: where are we in 2021?

Guillaume Desoubeaux, Adélaïde Chesnay
Frontiers in Bioscience-Landmark Volume 26 Issue 9, pp.409-412
Managing Editor: Graham Pawelec
DOI: 10.52586/4955 Published: 30 September 2021
Open Access
Article

Changes in growth performance, plasma metabolite concentrations, and myogenic gene expression in growing pigs fed a methionine-restricted diet

Zhongyue Yang, Md Shamimul Hasan, Rebecca M. Humphrey, John K. Htoo, Shengfa F. Liao
Frontiers in Bioscience-Landmark Volume 26 Issue 9, pp.413-422
Managing Editor: Graham Pawelec
DOI: 10.52586/4956 Published: 30 September 2021
Open Access
Article

Gas chromatography-mass spectrometry metabolic profiling, molecular simulation and dynamics of diverse phytochemicals of Punica granatum L. leaves against estrogen receptor

Talambedu Usha, Sushil Kumar Middha, Dhivya Shanmugarajan, Dinesh Babu, Arvind Kumar Goyal, Hasan Soliman Yusufoglu, Kora Rudraiah Sidhalinghamurthy
Frontiers in Bioscience-Landmark Volume 26 Issue 9, pp.423-441
Managing Editor: Biswaranjan Paital
DOI: 10.52586/4957 Published: 30 September 2021
Open Access
Article

Impact of intravenous iron on cardiac and skeletal oxidative stress and cardiac mitochondrial function in experimental uraemia chronic kidney disease

Sunil Bhandari
Frontiers in Bioscience-Landmark Volume 26 Issue 9, pp.442-464
Managing Editor: Hongwei Yao
DOI: 10.52586/4958 Published: 30 September 2021
Open Access
Article

Characterization of the differential efficacy of austenitic vs martensitic NiTi rotary files in non-surgical root canal retreatment: a micro-CT analysis

Loai Alsofi, Wael Rajkhan, Mey Al-Habib, Hebah Ashe, Yousef Alnowailaty, Khaled Balto
Frontiers in Bioscience-Landmark Volume 26 Issue 9, pp.465-474
DOI: 10.52586/4959 Published: 30 September 2021
Open Access
Article

Molecular subtype classification of breast cancer using established radiomic signature models based on 18F-FDG PET/CT images

Jianjing Liu, Haiman Bian, Yufan Zhang, Yongchang Gao, Guotao Yin, Ziyang Wang, Xiaofeng Li, Wenjuan Ma, Wengui Xu
Frontiers in Bioscience-Landmark Volume 26 Issue 9, pp.475-484
Managing Editor: Chuanjin Wu
DOI: 10.52586/4960 Published: 30 September 2021
Open Access
Article

Paeonol alleviates migration and invasion of endometrial stromal cells by reducing HIF-1α-regulated autophagy in endometriosis

Conghui Pang, Zhijuan Wu, Xiaoyan Xu, Wenxiu Yang, Xiaoxuan Wang, Yinghua Qi
Frontiers in Bioscience-Landmark Volume 26 Issue 9, pp.485-495
Managing Editor: Graham Pawelec
DOI: 10.52586/4961 Published: 30 September 2021
Open Access
Article

Clinical features, treatments, and outcomes of patients with anti-N-methyl-D-aspartate encephalitis—a single-center, retrospective analysis in China

Qianhui Xu, Yong Zhu, Qian Wang, Jing Han, Fengju Mao, Silin Zeng, Siyan Chen, Chenyong Zhao, Mei Gu, Zaiwang Li, Xiaoguang Luo, Xuejun Fu, Ying Huang
Frontiers in Bioscience-Landmark Volume 26 Issue 9, pp.496-503
DOI: 10.52586/4962 Published: 30 September 2021
Open Access
Article

Influences of blood flow parameters on temperature distribution during liver tumor microwave ablation

Jinying Wang, Shuicai Wu, Zeyi Wu, Hongjian Gao, Shengyang Huang
Frontiers in Bioscience-Landmark Volume 26 Issue 9, pp.504-516
Managing Editor: Graham Pawelec
DOI: 10.52586/4963 Published: 30 September 2021
Open Access
Article

PLA-based core-shell structure stereocomplexed nanoparticles with enhanced loading and release profile of paclitaxel

Yuemin Wang, Siyuan Cui, Bing Wu, Quanxing Zhang, Wei Jiang
Frontiers in Bioscience-Landmark Volume 26 Issue 9, pp.517-532
DOI: 10.52586/4964 Published: 30 September 2021
Open Access
Article

Effects of selenium application on biochemical characteristics and biofortification level of kohlrabi (Brassica oleracea L. var. gongylodes) produce

Marina Antoshkina, Nadezhda Golubkina, Agnieszka Sekara, Alessio Tallarita, Gianluca Сaruso
Frontiers in Bioscience-Landmark Volume 26 Issue 9, pp.533-542
Managing Editor: Grzegorz Bazylak
DOI: 10.52586/4965 Published: 30 September 2021
Open Access
Article

Foliar pathogen-induced assemblage of beneficial rhizosphere consortia increases plant defense against Setosphaeria turcica

Lin Zhu, Songhua Wang, Haiming Duan, Xiaomin Lu
Frontiers in Bioscience-Landmark Volume 26 Issue 9, pp.543-555
Managing Editor: Cheng Zhou, Afroz Alam
DOI: 10.52586/4966 Published: 30 September 2021
Open Access
Systematic Review

Assessing psychosocial interventions for informal caregivers of older people with early dementia: a systematic review of randomized controlled evidence

Shanshan Wang, Johanna de Almeida Mello, Anja Declercq
Frontiers in Bioscience-Landmark Volume 26 Issue 9, pp.556-571
Managing Editor: Graham Pawelec
DOI: 10.52586/4967 Published: 30 September 2021
Open Access
Review

Current strategies and technologies for finding drug targets of active components from traditional Chinese medicine

Feng Lu, Dan Wang, Ruo-Lan Li, Li-Ying He, Li Ai, Chun-Jie Wu
Frontiers in Bioscience-Landmark Volume 26 Issue 9, pp.572-589
Managing Editor: Josef Jampílek
DOI: 10.52586/4968 Published: 30 September 2021
Open Access
Review

The role of astrocytes in brain metastasis at the interface of circulating tumour cells and the blood brain barrier

Layla Burn, Nicholas Gutowski, Jacqueline Whatmore, Georgios Giamas, Md Zahidul Islam Pranjol
Frontiers in Bioscience-Landmark Volume 26 Issue 9, pp.590-601
Managing Editor: Michele Papa
DOI: 10.52586/4969 Published: 30 September 2021
Open Access
Review

Methylation alterations and advance of treatment in lymphoma

Meng-Ke Liu, Xiao-Jian Sun, Xiao-Dong Gao, Ying Qian, Li Wang, Wei-Li Zhao
Frontiers in Bioscience-Landmark Volume 26 Issue 9, pp.602-613
Managing Editor: Graham Pawelec
DOI: 10.52586/4970 Published: 30 September 2021
Open Access
Review

Neurodegeneration, memory loss, and dementia: the impact of biological clocks and circadian rhythm

Kenneth Maiese
Frontiers in Bioscience-Landmark Volume 26 Issue 9, pp.614-627
Managing Editor: Graham Pawelec
DOI: 10.52586/4971 Published: 30 September 2021
Open Access
Review

The renin-angiotensin system in central nervous system tumors and degenerative diseases

Simon Haron, Ethan J Kilmister, Paul F Davis, Stanley S Stylli, Theo Mantamadiotis, Andrew H Kaye, Sean R Hall, Swee T Tan, Agadha C Wickremesekera
Frontiers in Bioscience-Landmark Volume 26 Issue 9, pp.628-642
Managing Editor: Graham Pawelec
DOI: 10.52586/4972 Published: 30 September 2021
Open Access
Review

An overview of chia seed (Salvia hispanica L.) bioactive peptides’ derivation and utilization as an emerging nutraceutical food

Roshina Rabail, Moazzam Rafiq Khan, Hafiza Mahreen Mehwish, Muhammad Shahid Riaz Rajoka, Jose Manuel Lorenzo, Marek Kieliszek, Abdur Rauf Khalid, Muhammad Asim Shabbir, Rana Muhammad Aadil
Frontiers in Bioscience-Landmark Volume 26 Issue 9, pp.643-654
Managing Editor: Graham Pawelec
DOI: 10.52586/4973 Published: 30 September 2021
Open Access
Review

Advances in the regulation of plant development and stress response by miR167

Xia Liu, Sheng Huang, Hongtao Xie
Frontiers in Bioscience-Landmark Volume 26 Issue 9, pp.655-665
Managing Editor: Deyong Ren
DOI: 10.52586/4974 Published: 30 September 2021
Open Access
Mini-Review

Pregnancy, a unique case of heterochronic parabiosis and peripartum cardiomyopathy

Pascal J. Goldschmidt-Clermont, Corinne Hubinont, Alexander J.P. Goldschmidt, Darcy L. DiFede, Ian A. White
Frontiers in Bioscience-Landmark Volume 26 Issue 9, pp.666-672
Managing Editor: Graham Pawelec
DOI: 10.52586/4975 Published: 30 September 2021