Landmark Edition, Volume 26, 2021

Issue 1
Open Access
Review

Cell-centric hypotheses of aging

Siamak Tabibzadeh
Frontiers in Bioscience-Landmark Volume 26 Issue 1, pp.1-49
Managing Editor: Frontiers in Bioscience
DOI: 10.2741/4888 Published: 01 October 2020
Open Access
Review

Signaling pathways and effectors of aging

Siamak Tabibzadeh
Frontiers in Bioscience-Landmark Volume 26 Issue 1, pp.50-96
Managing Editor: Frontiers in Bioscience
DOI: 10.2741/4889 Published: 01 October 2020
Open Access
Review

From genoprotection to rejuvenation

Siamak Tabibzadeh
Frontiers in Bioscience-Landmark Volume 26 Issue 1, pp.97-162
Managing Editor: Frontiers in Bioscience
DOI: 10.2741/4890 Published: 01 October 2020
Open Access
Review

Self-renewal and differentiation of spermatogonial stem cells

Susha K Subash, Pradeep G Kumar
Frontiers in Bioscience-Landmark Volume 26 Issue 1, pp.163-205
DOI: 10.2741/4891 Published: 01 October 2020
Issue 2
Open Access
Review

Current treatment paradigms and emerging therapies for NAFLD/NASH

Sana Raza, Sangam Rajak, Aditya Upadhyay, Archana Tewari, Rohit Anthony Sinha
Frontiers in Bioscience-Landmark Volume 26 Issue 2, pp.206-237
Managing Editor: Frontiers in Bioscience
DOI: 10.2741/4892 Published: 01 October 2020
Open Access
Review

EMT imparts cancer stemness and plasticity: new perspectives and therapeutic potential

Sayoni Roy, Raghava R Sunkara, Manan Y Parmar, Saima Shaikh, Sanjeev K Waghmare
Frontiers in Bioscience-Landmark Volume 26 Issue 2, pp.238-265
DOI: 10.2741/4893 Published: 01 October 2020
Open Access
Article

Production of engineered cartilage from mesenchymal stem cell spheroids

Ha Thi-Ngan Le, Ngoc Bich Vu, Phuc Dang-Ngoc Nguyen, Thuy Thi-Thanh Dao, Xuan Hoang-Viet To, Phuc Van Pham
Frontiers in Bioscience-Landmark Volume 26 Issue 2, pp.266-285
Managing Editor: Phuc Van Pham
DOI: 10.2741/4894 Published: 01 October 2020
Open Access
Review

Neuroendocrine effects of cadmium exposure on male reproductive functions

Marcela Arteaga-Silva, Edith Arenas-Rios, Herlinda Bonilla-Jaime, Pablo Damian-Matzumura, Ofelia Limon-Morales, Joel Hernandez-Rodriguez, Darla Marquez-Aguiluz
Frontiers in Bioscience-Landmark Volume 26 Issue 2, pp.286-326
DOI: 10.2741/4895 Published: 01 October 2020
Open Access
Review

Health risk of heavy metals in street dust

Anahi Aguilera, Francisco Bautista, Avto Goguitchaichvili, Felipe Garcia-Oliva
Frontiers in Bioscience-Landmark Volume 26 Issue 2, pp.327-345
DOI: 10.2741/4896 Published: 01 October 2020
Open Access
Review

Bisphenol A: an endocrine-disruptor compound that modulates the immune response to infections

Victor Hugo Del Rio Araiza, Mariana Segovia-Mendoza, Karen Elizabeth Nava Castro, Samira Muñoz Cruz, Karina Chavez Rueda, Carmen Tlazoelteot Gomez de Leon, Jorge Morales Montor
Frontiers in Bioscience-Landmark Volume 26 Issue 2, pp.346-362
DOI: 10.2741/4897 Published: 01 October 2020
Open Access
Review

Impact of BPA on behavior, neurodevelopment and neurodegeneration

Daniela Rebolledo-Solleiro, Laura Y Castillo Flores, Helena Solleiro-Villavicencio
Frontiers in Bioscience-Landmark Volume 26 Issue 2, pp.363-400
DOI: 10.2741/4898 Published: 01 October 2020
Issue 3
Open Access
Review

Environmental pollutants: an immunoendocrine perspective on phthalates

Margarita Isabel Palacios-Arreola, Jorge Morales-Montor, Cintia Jocelyn Cazares-Martinez, Sandra Gomez-Arroyo, Karen Elizabeth Nava-Castro
Frontiers in Bioscience-Landmark Volume 26 Issue 3, pp.401-430
DOI: 10.2741/4899 Published: 01 October 2020
Open Access
Review

Environmental parasitology and its impact on the host nueroimmunoendocrine network

Carmen T Gomez de Leon, Pedro Ostoa-Saloma, Mariana Segovia-Mendoza, Victor H Del Rio-Araiza, Jorge Morales-Montor
Frontiers in Bioscience-Landmark Volume 26 Issue 3, pp.431-443
DOI: 10.2741/4900 Published: 01 October 2020
Open Access
Review

Crosstalk between CML cells with HUVECs and BMSCs through exosomes

Zafer Cetin, Eyup I. Saygili, Mehmet Yilmaz
Frontiers in Bioscience-Landmark Volume 26 Issue 3, pp.444-467
Managing Editor: Alex Georgakilas
DOI: 10.2741/4901 Published: 01 October 2020
Open Access
Review

Feed your microbiome and your heart: The gut-heart axis

Aaron Lerner, Christian Steigerwald, Torsten Matthias
Frontiers in Bioscience-Landmark Volume 26 Issue 3, pp.468-477
Managing Editor: Frontiers in Bioscience
DOI: 10.2741/4902 Published: 01 October 2020
Open Access
Review

Microbiomics and cloud-based analytics advance sustainable soil management

Anupam J. Das, Renuka Ravinath, Budiyal Ramesh Shilpa, Bilgi Sampgod Rohith, Arvind Kumar Goyal, Nijalingappa Ramesh, Mothukapalli Krishnareddy Prasannakumar, Hemavathy Ekambaram, Talambedu Usha, Sushil Kumar Middha
Frontiers in Bioscience-Landmark Volume 26 Issue 3, pp.478-495
Managing Editor: Biswaranjan Paital
DOI: 10.2741/4903 Published: 01 October 2020
Open Access
Review

Optimum health and inhibition of cancer progression by microbiome and resveratrol

James Stokes III, Sankalp Vinayak, Jazalyn Williams, Shalie Malik, Rajesh Singh, Upender Manne, Taofeek K. Owonikoko, Manoj K. Mishra
Frontiers in Bioscience-Landmark Volume 26 Issue 3, pp.496-517
Managing Editor: Indrajit Chowdhury
DOI: 10.2741/4904 Published: 01 October 2020
Open Access
Review

Diagnostic and therapeutic applications of smart nanocomposite dendrimers

Vinay Kumar, Rakesh K. Sahoo, Trambak Basak, Tanjina Yasmin, Umesh Gupta, Amit K. Goyal
Frontiers in Bioscience-Landmark Volume 26 Issue 3, pp.518-536
DOI: 10.2741/4905 Published: 01 October 2020
Open Access
Article

Corylus avellana L. modulates neurobehaviour and brain chemistry following high-fat diet

Anthony T Olofinnade, Adejoke Y Onaolapo, Olakunle J Onaolapo, Olugenga A Olowe, Adriano Mollica, Gokhan Zengin, Azurra Stefanucci
Frontiers in Bioscience-Landmark Volume 26 Issue 3, pp.537-551
Managing Editor: Frontiers in Bioscience
DOI: 10.2741/4906 Published: 01 October 2020
Open Access
Article

Nanog promotes stem-like traits of glioblastoma cells

Yuan Ye, Mengsi Zhang, Guangning Yan, Qinghua Ma, Zexuan Yan, Lihong Wang, Kaidi Yang, Deyu Guo
Frontiers in Bioscience-Landmark Volume 26 Issue 3, pp.552-565
Managing Editor: Li Liu
DOI: 10.2741/4907 Published: 01 October 2020
Open Access
Review

Impact of vitamin D on neurocognitive function in dementia, depression, schizophrenia and ADHD

Nithila Mariam Roy, Lara Al-Harthi, Neela Sampat, Rawan Al-Mujaini, Sangeetha Mahadevan, Samir Al Adawi, Musthafa Mohamed Essa, Lyutha Al Subhi, Buthaina Al-Balushi, M. Walid Qoronfleh
Frontiers in Bioscience-Landmark Volume 26 Issue 3, pp.566-611
DOI: 10.2741/4908 Published: 01 October 2020
Issue 4
Open Access
Review

Lamiaceae in the treatment of cardiovascular diseases

Francesca Patrignani, Sahdeo Prasad, Miroslav Novakovic, Petar D Marin, Danka Bukvicki
Frontiers in Bioscience-Landmark Volume 26 Issue 4, pp.612-643
DOI: 10.2741/4909 Published: 01 October 2020
Open Access
Article

Association between nitrated lipoproteins and vascular function in type 2 diabetes

Ajibola Adedayo, Ayobami Eluwole, Fasika Tedla, Arye Kremer, Nicole Mastrogiovanni, Muhammad Khan, Carl Rosenberg, Paul Dreizen, John La Rosa, Louis Salciccioli, Mohamed Boutjdir, Mary Ann Banerji, Clinton Brown, Moro Salifu, Jason Lazar, Ahmed Bakillah
Frontiers in Bioscience-Landmark Volume 26 Issue 4, pp.644-663
DOI: 10.2741/4910 Published: 01 October 2020
Open Access
Article

Studies in molecular modeling, in vitro CDK2 inhibition and antimetastatic activity of some synthetic flavones

Ojas S. Wagal, Akshada J. Joshi, Urmila J. Joshi, Heena R. Bhojwani, Khushboo V. Begwani, Harshank A. Dawne, Rajiv P. Gude, Sadhana S. Sathaye, Divya M. Kanchan
Frontiers in Bioscience-Landmark Volume 26 Issue 4, pp.664-681
DOI: 10.2741/4911 Published: 01 October 2020
Open Access
Article

ITGBL1 promotes gastric cancer cell proliferation and invasion via Akt signal pathway

Feng-yan Yin, Huan-peng Qi, ui Qiao, Xiao-hong Lv, Hai-hua Tan
Frontiers in Bioscience-Landmark Volume 26 Issue 4, pp.682-691
Managing Editor: Li Liu
DOI: 10.2741/4912 Published: 01 October 2020
Open Access
Article

Prognostic gene profiles in the tumor microenvironment of ovarian serous adenocarcinoma

Ruyue Tian, Guiping Zhao, Anni Zhou, Huihui Li, Bangwei Cao, Shuilong Guo
Frontiers in Bioscience-Landmark Volume 26 Issue 4, pp.692-705
Managing Editor: Li Liu
DOI: 10.2741/4913 Published: 01 October 2020
Open Access
Review

Role of cyclooxygenase-2 in colorectal cancer

Neha Nanda, Devinder K Dhawan
Frontiers in Bioscience-Landmark Volume 26 Issue 4, pp.706-716
DOI: 10.2741/4914 Published: 01 October 2020
Open Access
Review

MTiness in pseudo-malignant behavior of trophoblasts during embryo implantation

Ruby Dhar, Sunil Singh, Indrani Mukherjee, Karthikeyan Pethusamy, Kakali Purkayastha, Prasenjit Das, Jai Bhagwan Sharma, Radhey Shyam Sharma, Subhradip Karmakar
Frontiers in Bioscience-Landmark Volume 26 Issue 4, pp.717-743
DOI: 10.2741/4915 Published: 01 October 2020
Open Access
Review

Hydrolysis of chiral organophosphorus compounds by phosphotriesterases and mammalian paraoxonase-1

Antonio Monroy-Noyola, Damianys Almenares-Lopez, Eugenio Vilanova Gisbert
Frontiers in Bioscience-Landmark Volume 26 Issue 4, pp.744-770
DOI: 10.2741/4916 Published: 01 October 2020
Open Access
Review

Emerging roles of microRNAs in the regulation of Toll-like receptor (TLR)-signaling

Saswati Banerjee, Winston E. Thompson, Indrajit Chowdhury
Frontiers in Bioscience-Landmark Volume 26 Issue 4, pp.771-796
Managing Editor: Indrajit Chowdhury
DOI: 10.2741/4917 Published: 01 October 2020
Open Access
Review

Synesthesia, hallucination, and autism

Rocco J. Gennaro
Frontiers in Bioscience-Landmark Volume 26 Issue 4, pp.797-809
DOI: 10.2741/4918 Published: 01 October 2020
Issue 5
Open Access
Article

Analgesic effect of dl-THP on inflammatory pain mediated by suppressing spinal TRPV1 and P2X3 receptors in rats

Yan Wang, Rui-Rui Wang, Wei Sun, Chao Lou, Fan Yang, Ting He, Xiao-Liang Wang, Fa-Le Cao, Jun Chen
Frontiers in Bioscience-Landmark Volume 26 Issue 5, pp.1-10
Managing Editor: Frontiers in Bioscience
DOI: 10.52586/4919 Published: 30 April 2021
Open Access
Article

Diet-­induced differential effects on plasma lipids secretion by the inositol­-requiring transmembrane kinase/endoribonuclease 1α

Jahangir Iqbal, Ali Al Qarni, Ahmed Bakillah
Frontiers in Bioscience-Landmark Volume 26 Issue 5, pp.11-21
DOI: 10.52586/4920 Published: 30 April 2021
Open Access
Review

Microorganisms and cardiovascular diseases: importance of gut bacteria

Rashed Noor, Adiba Naz, Syeda Muntaka Maniha, Nafisa Tabassum, Tasmin Tabassum, Tahsin Tabassum, Masuma Afrin Taniya, Muntasir Billah
Frontiers in Bioscience-Landmark Volume 26 Issue 5, pp.22-28
Managing Editor: Muntasir Billah
DOI: 10.52586/4921 Published: 30 April 2021
Open Access
Review

Comparative review on left-handed Z-DNA

Reetabrita Roy, Pallab Chakraborty, Arindam Chatterjee, Joy Sarkar
Frontiers in Bioscience-Landmark Volume 26 Issue 5, pp.29-35
Managing Editor: Frontiers in Bioscience
DOI: 10.52586/4922 Published: 30 April 2021
Open Access
Review

The role of circular RNAs in brain and stroke

Yu-Ye Wang, Yan-Zhe Wang, He-Yu Zhang, Zhi-Yi He
Frontiers in Bioscience-Landmark Volume 26 Issue 5, pp.36-50
Managing Editor: Frontiers in Bioscience
DOI: 10.52586/4923 Published: 30 April 2021
Open Access
Review

Phytotherapy for treatment of cytokine storm in COVID-19

Leena Sapra, Asha Bhardwaj, Zaffar Azam, Deekhsha Madhry, Bhupendra Verma, Sumit Rathore, Rupesh K. Srivastava
Frontiers in Bioscience-Landmark Volume 26 Issue 5, pp.51-75
DOI: 10.52586/4924 Published: 30 April 2021
Open Access
Review

UPF1: a potential biomarker in human cancers

Bin-Lie Chen, Huai-Ming Wang, Xiao-Sheng Lin, Yong-Ming Zeng
Frontiers in Bioscience-Landmark Volume 26 Issue 5, pp.76-84
Managing Editor: Frontiers in Bioscience
DOI: 10.52586/4925 Published: 30 April 2021
Open Access
Review

Regulation of NOS expression in vascular diseases

Andrea Pautz, Huige Li, Hartmut Kleinert
Frontiers in Bioscience-Landmark Volume 26 Issue 5, pp.85-101
DOI: 10.52586/4926 Published: 30 April 2021
Issue 6
Open Access
Article

HSC70-JNK-BAG3 complex is critical for cardiomyocyte protection of BAG3 through its PXXP and BAG structural domains

Ling-Ling Zhao, Jiao-Na Gu, Xiao-Fang Zhu, Yin Hu, Hong Cao, Na Yao, Hua Sang, Bei-Bei Guo, Yu-Hang Wang, Hong-Yan Qian, Wei-Zhong Zhu
Frontiers in Bioscience-Landmark Volume 26 Issue 6, pp.102-113
Managing Editor: Frontiers in Bioscience
DOI: 10.52586/4927 Published: 30 May 2021
Open Access
Article

Acetylsalicylic acid improves cognitive performance in sleep deprived adult Zebrafish (Danio rerio) model

Muhammed Bishir, Muhammed Aslam, Abid Bhat, Bipul Ray, Preetham Elumalai, Jyothi Priya R, Luay Rashan, Jian Yang, Sulie L. Chang, Musthafa Mohamed Essa, Meena Kishore Sakharkar, Saravana Babu Chidambaram
Frontiers in Bioscience-Landmark Volume 26 Issue 6, pp.114-124
DOI: 10.52586/4928 Published: 30 May 2021
Open Access
Article

AGEs promote calcification of HASMCs by mediating Pi3k/AKT-GSK3β signaling

Qing-Chun Hou, Jun-Wei Wang, Gang Yuan, Yu-Ping Wang, Kai-Qiang Xu, Lei Zhang, Xiong-Fei Xu, Wei-Jian Mao, Yong Liu
Frontiers in Bioscience-Landmark Volume 26 Issue 6, pp.125-134
Managing Editor: Frontiers in Bioscience
DOI: 10.52586/4929 Published: 30 May 2021
Open Access
Review

Current knowledge about the connection between health status and gut microbiota from birth to elderly. A narrative review

Luigi Santacroce, Adrian Man, Ioannis Alexandros Charitos, Kastriot Haxhirexha, Skender Topi
Frontiers in Bioscience-Landmark Volume 26 Issue 6, pp.135-148
Managing Editor: Luigi Santacroce
DOI: 10.52586/4930 Published: 30 May 2021
Open Access
Review

A detailed review of the outbreak of COVID-19

Kabita Das, M. Shivapriya Pingali, Biswaranjan Paital, Falguni Panda, Samar Gourav Pati, Anirudh Singh, Pritish Kumar Varadwaj, Sintu Kumar Samanta
Frontiers in Bioscience-Landmark Volume 26 Issue 6, pp.149-170
Managing Editor: Biswaranjan Paital
DOI: 10.52586/4931 Published: 30 May 2021
Open Access
Review

Biosynthesis and extraction of high-value carotenoid from algae

Amit Kumar Gupta, Kunal Seth, Kirti Maheshwari, Prabhat Kumar Baroliya, Mukesh Meena, Ashwani Kumar, Vandana Vinayak, Harish
Frontiers in Bioscience-Landmark Volume 26 Issue 6, pp.171-190
Managing Editor: Ashwani Kumar
DOI: 10.52586/4932 Published: 30 May 2021
Issue 7
Open Access
Article

Association between isotretinoin (Roaccutanne) use and changes in periodontal clinical parameters and MMP-8 and MMP-9 salivary levels

Reham N. AlJasser, Razaan S. Alaqeely, Ibrahim A. Al-Hoqail, Mohammed Al-Haddab, Sadeem S. AlQahtani, Manal E. AlKenani, Afnan M. AlZahrani, Saleh AlOraini
Frontiers in Bioscience-Landmark Volume 26 Issue 7, pp.191-197
Managing Editor: Sarhang Sarwat Gul
DOI: 10.52586/4933 Published: 30 July 2021
Open Access
Article

Can commercial automated immunoassays be utilized to predict neutralizing antibodies after SARS-CoV-2 infection? A comparative study between three different assays

Ahmed Ismail, Farah M. Shurrab, Hadeel T. Al-Jighefee, Duaa W. Al-Sadeq, Hamda Qotba, Ibrahim Abdu Al-Shaar, Hadi. M. Yassine, Laith J. Abu-Raddad, Gheyath K. Nasrallah
Frontiers in Bioscience-Landmark Volume 26 Issue 7, pp.198-206
Managing Editor: Agnieszka Paradowska-Gorycka
DOI: 10.52586/4934 Published: 30 July 2021
Open Access
Article

Prediction of diabetic protein markers based on an ensemble method

Kaiyang Qu, Quan Zou, Hua Shi
Frontiers in Bioscience-Landmark Volume 26 Issue 7, pp.207-221
Managing Editor: Wei Lan
DOI: 10.52586/4935 Published: 30 July 2021
Open Access
Article

Improved prediction of drug-target interactions based on ensemble learning with fuzzy local ternary pattern

Zheng-Yang Zhao, Wen-Zhun Huang, Xin-Ke Zhan, Yu-An Huang, Shan-Wen Zhang, Chang-Qing Yu
Frontiers in Bioscience-Landmark Volume 26 Issue 7, pp.222-234
DOI: 10.52586/4936 Published: 30 July 2021
Open Access
Systematic Review

Nodal tumor volume as a prognostic factor for head and neck squamous cell carcinoma: a systematic review

Paris T. Moumoulidis, Athanasia Pavlopoulou, Reşat Ünal, Ifigeneia Mavragani, Alexandros G. Georgakilas, Efthymios Kyrodimos
Frontiers in Bioscience-Landmark Volume 26 Issue 7, pp.235-245
Managing Editor: Alfonso Urbanucci
DOI: 10.52586/4937 Published: 30 July 2021
Open Access
Review

Key toolkits of non-pharmacological management in COPD: during and beyond COVID-19

Jaber S. Alqahtani, Saeed M Alghamdi, Abdulelah M Aldhahir, Malik Althobiani, Tope Oyelade
Frontiers in Bioscience-Landmark Volume 26 Issue 7, pp.246-252
Managing Editor: Graham Pawelec
DOI: 10.52586/4938 Published: 30 July 2021
Issue 8
Open Access
Editorial

Serotonin is a multifaceted player in the immune response

Ling Lin, Kebin Hu
Frontiers in Bioscience-Landmark Volume 26 Issue 8, pp.253-254
Managing Editor: Graham Pawelec
DOI: 10.52586/4939 Published: 30 August 2021
Open Access
Editorial

New strategies in plastic surgery: autologous adipose-derived mesenchymal stem cells contained in fat grafting improves symptomatic scars

Pietro Gentile
Frontiers in Bioscience-Landmark Volume 26 Issue 8, pp.255-257
Managing Editor: Graham Pawelec
DOI: 10.52586/4940 Published: 30 August 2021
Open Access
Editorial

The long and short of it: long noncoding RNAs in neural development and diseases

Jinwei Zhang
Frontiers in Bioscience-Landmark Volume 26 Issue 8, pp.258-261
Managing Editor: Graham Pawelec
DOI: 10.52586/4941 Published: 30 August 2021
Open Access
Article

Effects of Telmisartan, an AT1 receptor antagonist, on mitochondria-specific genes expression in a mouse MPTP model of Parkinsonism

Bipul Ray, Girish Ramesh, Sudhir Rama Verma, Srinivasan Ramamurthy, Sunanda Tuladhar, Arehally Marappa Mahalakshmi, Musthafa Mohamed Essa, Saravana Babu Chidambaram
Frontiers in Bioscience-Landmark Volume 26 Issue 8, pp.262-271
DOI: 10.52586/4942 Published: 30 August 2021
Open Access
Article

Comprehensive evaluation of protein-coding sORFs prediction based on a random sequence strategy

Jiafeng Yu, Li Guo, Xianghua Dou, Wenwen Jiang, Bowen Qian, Jian Liu, Jun Wang, Chunling Wang, Congmin Xu
Frontiers in Bioscience-Landmark Volume 26 Issue 8, pp.272-278
Managing Editor: Leyi Wei, Jinwei Zhang
DOI: 10.52586/4943 Published: 30 August 2021
Open Access
Article

Bioinformatic approaches to the investigation of the atavistic genes implicated in cancer

Aikaterini Louka, Işıl Takan, Athanasia Pavlopoulou, Alexandros G. Georgakilas
Frontiers in Bioscience-Landmark Volume 26 Issue 8, pp.279-311
Managing Editor: Graham Pawelec
DOI: 10.52586/4944 Published: 30 August 2021
Open Access
Article

Evaluation of the efficiency of the imperative ecological remediation regarding tree growth, root development, and edaphic properties after Typhoon Hato (2017) in Zhuhai, China

Chi Zhang, Wanhui Qian, Lei Song, Dongxian Xu, Qing Zhao
Frontiers in Bioscience-Landmark Volume 26 Issue 8, pp.312-321
DOI: 10.52586/4945 Published: 30 August 2021
Open Access
Article

PLOD1 promotes cell growth and aerobic glycolysis by regulating the SOX9/PI3K/Akt/mTOR signaling pathway in gastric cancer

Yixin Zhang, Yingjie Wu, Xiaobao Su
Frontiers in Bioscience-Landmark Volume 26 Issue 8, pp.322-334
Managing Editor: Frontiers in Bioscience
DOI: 10.52586/4946 Published: 30 August 2021
Open Access
Article

Rictor is involved in Ctnnd2 deletion-induced impairment of spatial learning and memory but not autism-like behaviors

Xiaoya Wang, Man Xu, Qingbao Xu, Feng Yang, Hui Tang, Chuan Shao, Luyi Wang, Yan Wang, Jing Deng, Shali Wang
Frontiers in Bioscience-Landmark Volume 26 Issue 8, pp.335-346
Managing Editor: Graham Pawelec
DOI: 10.52586/4947 Published: 30 August 2021
Open Access
Review

Smart drugs and neuroenhancement: what do we know?

Massimiliano Esposito, Giuseppe Cocimano, Federica Ministrieri, Giuseppe Li Rosi, Nunzio Di Nunno, Giovanni Messina, Francesco Sessa, Monica Salerno
Frontiers in Bioscience-Landmark Volume 26 Issue 8, pp.347-359
Managing Editor: Antoni Camins
DOI: 10.52586/4948 Published: 30 August 2021
Open Access
Review

Association of chromosome 6 open reading frame 106 in different cancers

Emad Kutbi, Hassan Alsaif, Shahad AlOtaiby, Saeed Baradwan
Frontiers in Bioscience-Landmark Volume 26 Issue 8, pp.360-369
Managing Editor: Taeg Kyu Kwon,Amancio Carnero Moya
DOI: 10.52586/4949 Published: 30 August 2021
Open Access
Review

Kinesin superfamily proteins: roles in osteosarcoma

Yao Lu, Tao Song, Xue Xue, Gaolu Cao, Panpan Huang
Frontiers in Bioscience-Landmark Volume 26 Issue 8, pp.370-378
Managing Editor: Falasca Marco
DOI: 10.52586/4950 Published: 30 August 2021
Open Access
Commentary

Challenges at the host-arthropod-coronavirus interface and COVID-19: a One Health approach

José de la Fuente, Isabel G. Fernández de Mera, Christian Gortázar
Frontiers in Bioscience-Landmark Volume 26 Issue 8, pp.379-386
Managing Editor: Jiayue Yan
DOI: 10.52586/4951 Published: 30 August 2021
Open Access
Commentary

Possible causes of Parkinson’s disease

James D. Adams
Frontiers in Bioscience-Landmark Volume 26 Issue 8, pp.387-394
Managing Editor: Michele Papa, Xudong Huang
DOI: 10.52586/4952 Published: 30 August 2021
Open Access
Commentary

miR-634 inhibits human vascular smooth muscle cell proliferation and migration in hypertension through Wnt4/𝜷-catenin pathway

Ligang Niu, Na Sun, Lingheng Kong, Yan Xu, Yuming Kang
Frontiers in Bioscience-Landmark Volume 26 Issue 8, pp.395-404
Managing Editor: Alessandro Poggi
DOI: 10.52586/4953 Published: 30 August 2021
Issue 9
Open Access
Editorial

Clinical significance of inflammatory markers of bacterial infection in critically ill patients with COVID-19 after treatment with anti-inflammatory and immunomodulatory drugs: a complex new scenario

Daniele Roberto Giacobbe, Lorenzo Ball, Laura Magnasco, Chiara Dentone, Denise Battaglini, Chiara Robba, Paolo Pelosi, Matteo Bassetti
Frontiers in Bioscience-Landmark Volume 26 Issue 9, pp.405-408
Managing Editor: Alessandro Poggi
DOI: 10.52586/4954 Published: 30 September 2021
Open Access
Editorial

Health threat caused by fungi of medical interest: where are we in 2021?

Guillaume Desoubeaux, Adélaïde Chesnay
Frontiers in Bioscience-Landmark Volume 26 Issue 9, pp.409-412
Managing Editor: Graham Pawelec
DOI: 10.52586/4955 Published: 30 September 2021
Open Access
Article

Changes in growth performance, plasma metabolite concentrations, and myogenic gene expression in growing pigs fed a methionine-restricted diet

Zhongyue Yang, Md Shamimul Hasan, Rebecca M. Humphrey, John K. Htoo, Shengfa F. Liao
Frontiers in Bioscience-Landmark Volume 26 Issue 9, pp.413-422
Managing Editor: Graham Pawelec
DOI: 10.52586/4956 Published: 30 September 2021
Open Access
Article

Gas chromatography-mass spectrometry metabolic profiling, molecular simulation and dynamics of diverse phytochemicals of Punica granatum L. leaves against estrogen receptor

Talambedu Usha, Sushil Kumar Middha, Dhivya Shanmugarajan, Dinesh Babu, Arvind Kumar Goyal, Hasan Soliman Yusufoglu, Kora Rudraiah Sidhalinghamurthy
Frontiers in Bioscience-Landmark Volume 26 Issue 9, pp.423-441
Managing Editor: Biswaranjan Paital
DOI: 10.52586/4957 Published: 30 September 2021
Open Access
Article

Impact of intravenous iron on cardiac and skeletal oxidative stress and cardiac mitochondrial function in experimental uraemia chronic kidney disease

Sunil Bhandari
Frontiers in Bioscience-Landmark Volume 26 Issue 9, pp.442-464
Managing Editor: Hongwei Yao
DOI: 10.52586/4958 Published: 30 September 2021
Open Access
Article

Characterization of the differential efficacy of austenitic vs martensitic NiTi rotary files in non-surgical root canal retreatment: a micro-CT analysis

Loai Alsofi, Wael Rajkhan, Mey Al-Habib, Hebah Ashe, Yousef Alnowailaty, Khaled Balto
Frontiers in Bioscience-Landmark Volume 26 Issue 9, pp.465-474
DOI: 10.52586/4959 Published: 30 September 2021
Open Access
Article

Molecular subtype classification of breast cancer using established radiomic signature models based on 18F-FDG PET/CT images

Jianjing Liu, Haiman Bian, Yufan Zhang, Yongchang Gao, Guotao Yin, Ziyang Wang, Xiaofeng Li, Wenjuan Ma, Wengui Xu
Frontiers in Bioscience-Landmark Volume 26 Issue 9, pp.475-484
Managing Editor: Chuanjin Wu
DOI: 10.52586/4960 Published: 30 September 2021
Open Access
Article

Paeonol alleviates migration and invasion of endometrial stromal cells by reducing HIF-1α-regulated autophagy in endometriosis

Conghui Pang, Zhijuan Wu, Xiaoyan Xu, Wenxiu Yang, Xiaoxuan Wang, Yinghua Qi
Frontiers in Bioscience-Landmark Volume 26 Issue 9, pp.485-495
Managing Editor: Graham Pawelec
DOI: 10.52586/4961 Published: 30 September 2021
Open Access
Article

Clinical features, treatments, and outcomes of patients with anti-N-methyl-D-aspartate encephalitis—a single-center, retrospective analysis in China

Qianhui Xu, Yong Zhu, Qian Wang, Jing Han, Fengju Mao, Silin Zeng, Siyan Chen, Chenyong Zhao, Mei Gu, Zaiwang Li, Xiaoguang Luo, Xuejun Fu, Ying Huang
Frontiers in Bioscience-Landmark Volume 26 Issue 9, pp.496-503
DOI: 10.52586/4962 Published: 30 September 2021
Open Access
Article

Influences of blood flow parameters on temperature distribution during liver tumor microwave ablation

Jinying Wang, Shuicai Wu, Zeyi Wu, Hongjian Gao, Shengyang Huang
Frontiers in Bioscience-Landmark Volume 26 Issue 9, pp.504-516
Managing Editor: Graham Pawelec
DOI: 10.52586/4963 Published: 30 September 2021
Open Access
Article

PLA-based core-shell structure stereocomplexed nanoparticles with enhanced loading and release profile of paclitaxel

Yuemin Wang, Siyuan Cui, Bing Wu, Quanxing Zhang, Wei Jiang
Frontiers in Bioscience-Landmark Volume 26 Issue 9, pp.517-532
DOI: 10.52586/4964 Published: 30 September 2021
Open Access
Article

Effects of selenium application on biochemical characteristics and biofortification level of kohlrabi (Brassica oleracea L. var. gongylodes) produce

Marina Antoshkina, Nadezhda Golubkina, Agnieszka Sekara, Alessio Tallarita, Gianluca Сaruso
Frontiers in Bioscience-Landmark Volume 26 Issue 9, pp.533-542
Managing Editor: Grzegorz Bazylak
DOI: 10.52586/4965 Published: 30 September 2021
Open Access
Article

Foliar pathogen-induced assemblage of beneficial rhizosphere consortia increases plant defense against Setosphaeria turcica

Lin Zhu, Songhua Wang, Haiming Duan, Xiaomin Lu
Frontiers in Bioscience-Landmark Volume 26 Issue 9, pp.543-555
Managing Editor: Cheng Zhou, Afroz Alam
DOI: 10.52586/4966 Published: 30 September 2021
Open Access
Systematic Review

Assessing psychosocial interventions for informal caregivers of older people with early dementia: a systematic review of randomized controlled evidence

Shanshan Wang, Johanna de Almeida Mello, Anja Declercq
Frontiers in Bioscience-Landmark Volume 26 Issue 9, pp.556-571
Managing Editor: Graham Pawelec
DOI: 10.52586/4967 Published: 30 September 2021
Open Access
Review

Current strategies and technologies for finding drug targets of active components from traditional Chinese medicine

Feng Lu, Dan Wang, Ruo-Lan Li, Li-Ying He, Li Ai, Chun-Jie Wu
Frontiers in Bioscience-Landmark Volume 26 Issue 9, pp.572-589
Managing Editor: Josef Jampílek
DOI: 10.52586/4968 Published: 30 September 2021
Open Access
Review

The role of astrocytes in brain metastasis at the interface of circulating tumour cells and the blood brain barrier

Layla Burn, Nicholas Gutowski, Jacqueline Whatmore, Georgios Giamas, Md Zahidul Islam Pranjol
Frontiers in Bioscience-Landmark Volume 26 Issue 9, pp.590-601
Managing Editor: Michele Papa
DOI: 10.52586/4969 Published: 30 September 2021
Open Access
Review

Methylation alterations and advance of treatment in lymphoma

Meng-Ke Liu, Xiao-Jian Sun, Xiao-Dong Gao, Ying Qian, Li Wang, Wei-Li Zhao
Frontiers in Bioscience-Landmark Volume 26 Issue 9, pp.602-613
Managing Editor: Graham Pawelec
DOI: 10.52586/4970 Published: 30 September 2021
Open Access
Review

Neurodegeneration, memory loss, and dementia: the impact of biological clocks and circadian rhythm

Kenneth Maiese
Frontiers in Bioscience-Landmark Volume 26 Issue 9, pp.614-627
Managing Editor: Graham Pawelec
DOI: 10.52586/4971 Published: 30 September 2021
Open Access
Review

The renin-angiotensin system in central nervous system tumors and degenerative diseases

Simon Haron, Ethan J Kilmister, Paul F Davis, Stanley S Stylli, Theo Mantamadiotis, Andrew H Kaye, Sean R Hall, Swee T Tan, Agadha C Wickremesekera
Frontiers in Bioscience-Landmark Volume 26 Issue 9, pp.628-642
Managing Editor: Graham Pawelec
DOI: 10.52586/4972 Published: 30 September 2021
Open Access
Review

An overview of chia seed (Salvia hispanica L.) bioactive peptides’ derivation and utilization as an emerging nutraceutical food

Roshina Rabail, Moazzam Rafiq Khan, Hafiza Mahreen Mehwish, Muhammad Shahid Riaz Rajoka, Jose Manuel Lorenzo, Marek Kieliszek, Abdur Rauf Khalid, Muhammad Asim Shabbir, Rana Muhammad Aadil
Frontiers in Bioscience-Landmark Volume 26 Issue 9, pp.643-654
Managing Editor: Graham Pawelec
DOI: 10.52586/4973 Published: 30 September 2021
Open Access
Review

Advances in the regulation of plant development and stress response by miR167

Xia Liu, Sheng Huang, Hongtao Xie
Frontiers in Bioscience-Landmark Volume 26 Issue 9, pp.655-665
Managing Editor: Deyong Ren
DOI: 10.52586/4974 Published: 30 September 2021
Open Access
Mini-Review

Pregnancy, a unique case of heterochronic parabiosis and peripartum cardiomyopathy

Pascal J. Goldschmidt-Clermont, Corinne Hubinont, Alexander J.P. Goldschmidt, Darcy L. DiFede, Ian A. White
Frontiers in Bioscience-Landmark Volume 26 Issue 9, pp.666-672
Managing Editor: Graham Pawelec
DOI: 10.52586/4975 Published: 30 September 2021
Issue 10
Open Access
Editorial

Interaction of anti-diabetic medications and gut microbiota

Ru Chen, Sheng Pan
Frontiers in Bioscience-Landmark Volume 26 Issue 10, pp.673-674
Managing Editor: Frontiers in Bioscience
DOI: 10.52586/4976 Published: 30 October 2021
Open Access
Comment

Co-signaling surface receptors: regulators of adaptive immune response. Comment on Shen H, et al. "Co-signaling receptors regulate T-cell plasticity and immune tolerance". Frontiers in Bioscience-Landmark. 2019; 24: 96–132

Alessandro Poggi
Frontiers in Bioscience-Landmark Volume 26 Issue 10, pp.675-677
Managing Editor: Graham Pawelec
DOI: 10.52586/4977 Published: 30 October 2021
Open Access
Reply

Reply to Comment on Shen H, et al. “Co-signaling receptors regulate T-cell plasticity and immune tolerance”. Frontiers in Bioscience-Landmark. 2019; 24: 96–132

Haitao Shen, Na Wu, Gayani Nanayakkara, Hangfei Fu, Qian Yang, William Y. Yang, Angus Li, Yu Sun, Charles Drummer IV, Candice Johnson, Ying Shao, Luqiao Wang, Keman Xu, Wenhui Hu, Marion Chan, Vincent Tam, Eric T. Choi, Hong Wang, Xiaofeng Yang
Frontiers in Bioscience-Landmark Volume 26 Issue 10, pp.678-679
Managing Editor: Graham Pawelec
DOI: 10.52586/4978 Published: 30 October 2021
Open Access
Commentary

Is miR therapeutic targeting still a miRage?

Elena Levantini
Frontiers in Bioscience-Landmark Volume 26 Issue 10, pp.680-692
Managing Editor: Graham Pawelec
DOI: 10.52586/4979 Published: 30 October 2021
Open Access
Article

A phase II clinical trial with repeated intrathecal injections of autologous mesenchymal stem cells in patients with amyotrophic lateral sclerosis

Panayiota Petrou, Ibrahim Kassis, Nour Eddine Yaghmour, Ariel Ginzberg, Dimitrios Karussis
Frontiers in Bioscience-Landmark Volume 26 Issue 10, pp.693-706
Managing Editor: Graham Pawelec
DOI: 10.52586/4980 Published: 30 October 2021
Open Access
Article

Expression and prognosis analysis of JMJD5 in human cancers

Hui Li, Qun Li, Hong Jing, Jianghai Zhao, Hui Zhang, Xuhui Ma, Lunshou Wei, Rujiang Dai, Weihong Sun, Zhimin Suo
Frontiers in Bioscience-Landmark Volume 26 Issue 10, pp.707-716
Managing Editor: Graham Pawelec
DOI: 10.52586/4981 Published: 30 October 2021
Open Access
Article

Clinical features of pneumonia in severely malnourished children with diarrhoea compared to those without diarrhoea

Sufia Islam, Nishat Nasrin, Nigar Sultana Tithi, Christian Lehmann, Mohammod Jobayer Chisti
Frontiers in Bioscience-Landmark Volume 26 Issue 10, pp.717-722
Managing Editor: Graham Pawelec
DOI: 10.52586/4982 Published: 30 October 2021
Open Access
Article

Characterization of multiscale logic operations in the neural circuits

JunHyuk Woo, Kiri Choi, Soon Ho Kim, Kyungreem Han, MooYoung Choi
Frontiers in Bioscience-Landmark Volume 26 Issue 10, pp.723-739
Managing Editor: Graham Pawelec
DOI: 10.52586/4983 Published: 30 October 2021
Open Access
Article

Identification of key factors shaping integrated levels of ACE2 and TMPRSS2 expression in head and neck squamous cell carcinoma

Tianyu Zheng, Peipei Yue, Tongtong Han, Kaige Zhang, Yiming Jiang, Sijian Wang, Lulu Jiang, Baohong Zhao, Xinwen Zhang, Xu Yan
Frontiers in Bioscience-Landmark Volume 26 Issue 10, pp.740-751
Managing Editor: Graham Pawelec
DOI: 10.52586/4984 Published: 30 October 2021
Open Access
Article

Synthesis and analysis of small molecules to restrain the function of tissue factor within tumour cells

Oluremi I Adeniran, Mohammad A Mohammad, Sophie Featherby, Anthony Maraveyas, Andrew N Boa, Camille Ettelaie
Frontiers in Bioscience-Landmark Volume 26 Issue 10, pp.752-764
Managing Editor: Silvia S. Barbieri
DOI: 10.52586/4985 Published: 30 October 2021
Open Access
Article

Expression of MHC class I polypeptide-related sequence A (MICA) in colorectal cancer

Ingrid Espinoza, Sumit Agarwal, Marcelo Sakiyama, Veena Shenoy, Wayne S. Orr, Sameer Al Diffalha, Anna Prizment, Sooryanarayana Varambally, Upender Manne, Christian R. Gomez
Frontiers in Bioscience-Landmark Volume 26 Issue 10, pp.765-776
Managing Editor: Graham Pawelec
DOI: 10.52586/4986 Published: 30 October 2021
Open Access
Article

80MAP17 promotes the tumorigenesis of papillary thyroid carcinoma by reducing the stability of p53

Kun Yu, Hongjiang Lu, Yanhong Chen, Ying Xin, Zhuo Tan, Qiong Yang
Frontiers in Bioscience-Landmark Volume 26 Issue 10, pp.777-788
Managing Editor: Elena Levantini
DOI: 10.52586/4987 Published: 30 October 2021
Open Access
Article

Effective inhibition of coronavirus replication by Polygonum cuspidatum

Huan Xu, Jing Li, Shidong Song, Zhen Xiao, Xuanqing Chen, Boxuan Huang, Mengsi Sun, Guoqing Su, Demin Zhou, Guanyu Wang, Ran Hao, Na Wang
Frontiers in Bioscience-Landmark Volume 26 Issue 10, pp.789-798
Managing Editor: Alessandro Poggi
DOI: 10.52586/4988 Published: 30 October 2021
Open Access
Article

The biological effect of cobalt chloride mimetic-hypoxia on nucleus pulposus cells and the comparability with physical hypoxia in vitro

Xiao-Xin Gao, Chen-Hao Liu, Zhi-Lei Hu, Hai-Yin Li, Xian Chang, Yue-Yang Li, Yu-Yao Zhang, Yu Zhai, Chang-Qing Li
Frontiers in Bioscience-Landmark Volume 26 Issue 10, pp.799-812
Managing Editor: Guoyao Wu
DOI: 10.52586/4989 Published: 30 October 2021
Open Access
Article

Exploration of the active components and pharmacological mechanism of Compound Longmaining for the treatment of myocardial infarction

Jia Li, Xiao Wang, Diaodiao Bu, Junbo Zou, Shining Xun, Yao Wang, Yanzuo Jia, Shangshang Yu, Wenfei Wang, Jiahui Zheng, Jiejun Hou, Xiaofei Zhang, Changli Wang
Frontiers in Bioscience-Landmark Volume 26 Issue 10, pp.813-827
Managing Editor: Graham Pawelec
DOI: 10.52586/4990 Published: 30 October 2021
Open Access
Review

External visible characteristics prediction through SNPs analysis in the forensic setting: a review

Pamela Tozzo, Caterina Politi, Arianna Delicati, Andrea Gabbin, Luciana Caenazzo
Frontiers in Bioscience-Landmark Volume 26 Issue 10, pp.828-850
Managing Editor: Cristoforo Pomara
DOI: 10.52586/4991 Published: 30 October 2021
Open Access
Review

Nanomaterials in Alzheimer’s disease treatment: a comprehensive review

Maryam Faiyaz, Mohd. Azhardin Ganayee, Salman Akhtar, Saravanan Krishnan, Bableen Flora, Deeksha Dogra, Niraj Kumar Jha, Dinesh Kumar Chellappan, Poonam Negi, Kamal Dua, Kavindra Kumar Kesari, Piyush Kumar Gupta
Frontiers in Bioscience-Landmark Volume 26 Issue 10, pp.851-865
Managing Editor: Ghulam Md Ashraf
DOI: 10.52586/4992 Published: 30 October 2021
Open Access
Review

Tropism and transduction of oncolytic adenovirus vectors in prostate cancer therapy

Chuang Wu, Fu-kun Wei, Zi-yang Xu, Ru-min Wen, Jia-cun Chen, Jun-qi Wang, Li-jun Mao
Frontiers in Bioscience-Landmark Volume 26 Issue 10, pp.866-872
Managing Editor: Graham Pawelec
DOI: 10.52586/4993 Published: 30 October 2021
Open Access
Review

Comparative safety and efficacy of molecular-targeted drugs, immune checkpoint inhibitors, hepatic arterial infusion chemotherapy and their combinations in advanced hepatocellular carcinoma: findings from advances in landmark trials

Yangxun Pan, Ruojing Wang, Dandan Hu, Wa Xie, Yizhen Fu, Jiajie Hou, Li Xu, Yaojun Zhang, Minshan Chen, Zhongguo Zhou
Frontiers in Bioscience-Landmark Volume 26 Issue 10, pp.873-881
Managing Editor: Alessandro Poggi
DOI: 10.52586/4994 Published: 30 October 2021
Open Access
Review

Sarcopenia and perioperative management of elderly surgical patients

Yan Shi, Ling Zhou, Enshi Yan, Ling Yang, Chun Yang, Cunming Liu
Frontiers in Bioscience-Landmark Volume 26 Issue 10, pp.882-894
Managing Editor: Elisa Belluzzi
DOI: 10.52586/4995 Published: 30 October 2021
Open Access
Review

Ten-eleven translocation proteins (TETs): tumor suppressors or tumor enhancers?

Cuili Ma, Hwanwook Seong, Yumei Liu, Xiao Yu, Shuanliang Xu, Yujing Li
Frontiers in Bioscience-Landmark Volume 26 Issue 10, pp.895-915
Managing Editor: Graham Pawelec
DOI: 10.52586/4996 Published: 30 October 2021
Open Access
Review

Research progress in gene editing technology

Sheng Huang, Yali Yan, Fei Su, Xiaorui Huang, Dandan Xia, Xinxin Jiang, Yinghui Dong, Ping Lv, Fangyuan Chen, Yanwei Lv
Frontiers in Bioscience-Landmark Volume 26 Issue 10, pp.916-927
Managing Editor: Alexandros G. Georgakilas
DOI: 10.52586/4997 Published: 30 October 2021
Open Access
Review

Approaches for the amelioration of adverse effects of drought stress on crop plants

Anamika Dubey, Ashwani Kumar, Muneer Ahmad Malla, Kanika Chowdhary, Garima Singh, Gudasalamani Ravikanth, Harish, Satyawati Sharma, Zaki Saati-Santamaria, Esther Menéndez, Joanna Felicity Dames
Frontiers in Bioscience-Landmark Volume 26 Issue 10, pp.928-947
Managing Editor: Kevin Cianfaglione
DOI: 10.52586/4998 Published: 30 October 2021
Open Access
Review

Potential roles of mesenchymal stem cells and their exosomes in the treatment of COVID-19

Xiaoyun Cheng, Mao Jiang, Lingzhi Long, Jie Meng
Frontiers in Bioscience-Landmark Volume 26 Issue 10, pp.948-961
Managing Editor: Graham Pawelec
DOI: 10.52586/4999 Published: 30 October 2021
Issue 11
Open Access
Editorial

Environmental medicine and its impact on human health

Jorge Morales Montor
Frontiers in Bioscience-Landmark Volume 26 Issue 11, pp.962-964
Managing Editor: Graham Pawelec
DOI: 10.52586/5000 Published: 30 November 2021
Open Access
Article

Hyperglycemia results in significant pathophysiological changes of placental spiral artery remodeling and angiogenesis, further contributing to congenital defects

Yushu Qin, Naomi McCauley, Zehuan Ding, Lauren Lawless, Zhimin Liu, Ke Zhang, Linglin Xie
Frontiers in Bioscience-Landmark Volume 26 Issue 11, pp.965-976
Managing Editor: Graham Pawelec
DOI: 10.52586/5001 Published: 30 November 2021
Open Access
Article

Synergistic antimicrobial activity of a novel cationic micelle L/D2 and imipenem against multidrug-resistant Acinetobacter baumannii

Guansheng Zhong, Yingjiao Zhang, Kun Yu, Li Wen, Hongjiang Lu, Yang Zheng
Frontiers in Bioscience-Landmark Volume 26 Issue 11, pp.977-987
Managing Editor: Graham Pawelec
DOI: 10.52586/5002 Published: 30 November 2021
Open Access
Article

Functional mapping of gravitropism and phototropism for a desert tree, Populus euphratica

Peng Jiang, Nan Ma, Fengshuo Sun, Meixia Ye, Rongling Wu
Frontiers in Bioscience-Landmark Volume 26 Issue 11, pp.988-1000
Managing Editor: Changsoo Kim
DOI: 10.52586/5003 Published: 30 November 2021
Open Access
Article

Transcriptome profiling reveals gene regulation programs underlying tail development in the Ornamented Pygmy frog Microhyla fissipes

Shouhong Wang, Lusha Liu, Yun-Bo Shi, Jianping Jiang
Frontiers in Bioscience-Landmark Volume 26 Issue 11, pp.1001-1012
Managing Editor: Haseeb Ahmad Khan
DOI: 10.52586/5004 Published: 30 November 2021
Open Access
Article

Mechanical ventilation regulated the differentiation and proliferation of diaphragm satellite cells

Junying Ding, Qian Li, Feng Liang, Salyan Bhattarai, Qingquan Liu
Frontiers in Bioscience-Landmark Volume 26 Issue 11, pp.1013-1018
Managing Editor: Guoyao Wu
DOI: 10.52586/5005 Published: 30 November 2021
Open Access
Article

Co-expression modules construction by WGCNA and identify potential hub genes and regulation pathways of postpartum depression

Zhifang Deng, Wei Cai, Jue Liu, Aiping Deng, Yuan Yang, Jie Tu, Cheng Yuan, Han Xiao, Wenqi Gao
Frontiers in Bioscience-Landmark Volume 26 Issue 11, pp.1019-1030
Managing Editor: Graham Pawelec
DOI: 10.52586/5006 Published: 30 November 2021
Open Access
Article

Anti-Parkinson’s evaluation of Brassica juncea leaf extract and underlying mechanism of its phytochemicals

Uzma Saleem, Shabana Bibi, Muhammad Ajmal Shah, Bashir Ahmad, Ammara Saleem, Zunera Chauhdary, Fareeha Anwar, Nimra Javaid, Sundas Hira, Muhammad Furqan Akhtar, Ghulam Mujtaba Shah, Muhammad Saad Khan, Haji Muhammad, Muhammad Qasim, Mohammad Alqarni, Majed A. Algarni, Renald Blundell, Celia Vargas-De-La-Cruz, Oscar Herrera-Calderon, Reem Hasaballah Alhasani
Frontiers in Bioscience-Landmark Volume 26 Issue 11, pp.1031-1051
DOI: 10.52586/5007 Published: 30 November 2021
Open Access
Article

Aldosterone is a possible new stimulating factor for promoting vascular calcification

Xusheng Zhang, Xiaoou Zhou, Zhanjun Huang, Xiaorong Fan, Xiaoqing Tan, Chengzhi Lu, Jianshe Yang
Frontiers in Bioscience-Landmark Volume 26 Issue 11, pp.1052-1063
Managing Editor: Graham Pawelec
DOI: 10.52586/5008 Published: 30 November 2021
Open Access
Article

Association of COMT, BDNF and 5-HTT functional polymorphisms with personality characteristics

Marco Tommasi, Maria Rita Sergi, Fani Konstantinidou, Marica Franzago, Mirko Pesce, Irene La Fratta, Alfredo Grilli, Liborio Stuppia, Laura Picconi, Aristide Saggino, Valentina Gatta
Frontiers in Bioscience-Landmark Volume 26 Issue 11, pp.1064-1074
Managing Editor: Alexandros G. Georgakilas
DOI: 10.52586/5009 Published: 30 November 2021
Open Access
Article

Seed amplification assays for diagnosing synucleinopathies: the issue of influencing factors

Giovanni Bellomo, Silvia Paciotti, Leonardo Gatticchi, Domenico Rizzo, Federico Paolini Paoletti, Marco Fragai, Lucilla Parnetti
Frontiers in Bioscience-Landmark Volume 26 Issue 11, pp.1075-1088
DOI: 10.52586/5010 Published: 30 November 2021
Open Access
Article

Appraisal of the antimicrobial and cytotoxic potentials of nanoparticles biosynthesized from the extracts of Pelargonium quercetorum Agnew

Berrak Dumlupınar, Gökçe Şeker Karatoprak, Mehmet Fırat, Esra Küpeli Akkol
Frontiers in Bioscience-Landmark Volume 26 Issue 11, pp.1089-1096
Managing Editor: Zhigang Zhang
DOI: 10.52586/5011 Published: 30 November 2021
Open Access
Article

The global, regional, and national burden of laryngeal cancer and the attributable risk factors in all countries and territories during 2007–2017

Zhisen Shen, Jun Li, Lin Luo, Liyuan Han
Frontiers in Bioscience-Landmark Volume 26 Issue 11, pp.1097-1105
Managing Editor: Graham Pawelec
DOI: 10.52586/5012 Published: 30 November 2021
Open Access
Article

The killing effect of Tanshinol on breast cancer cells: insight into the reversion of TGF-𝜷1-mediated suppression of NK cell functions

Chunmei Yang, Cheng Qian, Tingting Zhang, Weiwei Zheng, Shan Zhang, Shijun Wang, Aiyun Wang, Yang Zhao, Yin Lu
Frontiers in Bioscience-Landmark Volume 26 Issue 11, pp.1106-1118
Managing Editor: Graham Pawelec
DOI: 10.52586/5013 Published: 30 November 2021
Open Access
Article

Genome-wide comparative analysis of transposable elements in Palmae genomes

Mohanad A. Ibrahim, Badr M. Al-Shomrani, Sultan N. Alharbi, Tyler A. Elliott, Mohammed S. Alsuabeyl, Fahad H. Alqahtani, Manee M. Manee
Frontiers in Bioscience-Landmark Volume 26 Issue 11, pp.1119-1131
Managing Editor: Changsoo Kim
DOI: 10.52586/5014 Published: 30 November 2021
Open Access
Article

Short and long-term effects of high-intensity interval training applied alone or with whole-body cryostimulation on glucose homeostasis and myokine levels in overweight to obese subjects

Marta Kozłowska-Flis, Ewa Rodziewicz-Flis, Katarzyna Micielska, Jakub Kortas, Joanna Jaworska, Andżelika Borkowska, Veronica Sansoni, Silvia Perego, Giovanni Lombardi, Ewa Ziemann
Frontiers in Bioscience-Landmark Volume 26 Issue 11, pp.1132-1146
Managing Editor: Pietro Gentile
DOI: 10.52586/5015 Published: 30 November 2021
Open Access
Article

Novel insights into the role of 5-Methylcytosine RNA methylation in human abdominal aortic aneurysm

Yuchen He, Hao Zhang, Fanxing Yin, Panpan Guo, Shiyue Wang, Yihao Wu, Shijie Xin, Yanshuo Han, Jian Zhang
Frontiers in Bioscience-Landmark Volume 26 Issue 11, pp.1147-1165
Managing Editor: Alexandros G. Georgakilas
DOI: 10.52586/5016 Published: 30 November 2021
Open Access
Article

A new ultrasound-guided percutaneous electrolysis and exercise treatment in patellar tendinopathy: three case reports

Alberto Carlos Muñoz Fernández, Carlos Barragán Carballar, Jorge Hugo Villafañe, Sebastián Martín Pérez, José Luis Alonso Pérez, Raquel Díaz-Meco, David García Jiménez, Eleuterio A. Sánchez Romero
Frontiers in Bioscience-Landmark Volume 26 Issue 11, pp.1166-1175
Managing Editor: Graham Pawelec
DOI: 10.52586/5017 Published: 30 November 2021
Open Access
Article

Identification of candidate biomarker EMP3 and its prognostic potential in clear cell renal cell carcinoma

Qingyang Lv, Wen Xiao, Zhiyong Xiong, Jian Shi, Daojia Miao, Xiangui Meng, Hongwei Yuan, Hongmei Yang, Xiaoping Zhang
Frontiers in Bioscience-Landmark Volume 26 Issue 11, pp.1176-1190
Managing Editor: Graham Pawelec
DOI: 10.52586/5018 Published: 30 November 2021
Open Access
Article

The predictive potential of genetic single nucleotide polymorphisms in CBX4 for hepatocellular carcinoma survival

Xiao-Ying Zhu, Mei-Jin Huang, Qun-Ying Su, Xiang-Zhizi Wang, Juan Wang, Qin-Qin Long, Xue-Min Wu, Xiao-Ying Huang, Jin-Guang Yao, Xi-Dai Long
Frontiers in Bioscience-Landmark Volume 26 Issue 11, pp.1191-1203
Managing Editor: Jian Zhang
DOI: 10.52586/5019 Published: 30 November 2021
Open Access
Review

Non-invasive, non-pharmacological/bio-technological interventions towards neurorestoration upshot after ischemic stroke, in adults—systematic, synthetic, literature review

Gelu Onose, Aurelian Anghelescu, Corneliu Dan Blendea, Vlad Ciobanu, Cristina Octaviana Daia, Florentina Carmen Firan, Constantin Munteanu, Mihaela Oprea, Aura Spinu, Cristina Popescu
Frontiers in Bioscience-Landmark Volume 26 Issue 11, pp.1204-1239
Managing Editor: Michele Papa
DOI: 10.52586/5020 Published: 30 November 2021
Open Access
Review

An updated overview of the physiological and molecular responses of rice to anoxia

Malay Kumar Adak, Indraneel Saha, Debabrata Dolui, Mirza Hasanuzzaman
Frontiers in Bioscience-Landmark Volume 26 Issue 11, pp.1240-1255
Managing Editor: Changsoo Kim
DOI: 10.52586/5021 Published: 30 November 2021
Open Access
Review

Discovery of novel peptide neurotoxins from sea anemone species

Jinxing Fu, Yanling Liao, Ai-Hua Jin, Bingmiao Gao
Frontiers in Bioscience-Landmark Volume 26 Issue 11, pp.1256-1273
Managing Editor: Graham Pawelec
DOI: 10.52586/5022 Published: 30 November 2021
Open Access
Review

Multidisciplinary of anti-COVID-19 battle: from immunological weapons to ecological interventions

Federico Boem, Giulia Nannini, Amedeo Amedei
Frontiers in Bioscience-Landmark Volume 26 Issue 11, pp.1274-1285
Managing Editor: Graham Pawelec
DOI: 10.52586/5023 Published: 30 November 2021
Open Access
Review

Immunogenicity and safety of SARS-CoV-2 vaccines in clinical trials

Hui Xuan Lim, Masita Arip, Abdul Aziz Al-Fattah Yahaya, Seyed Davoud Jazayeri, Sibrandes Poppema, Chit Laa Poh
Frontiers in Bioscience-Landmark Volume 26 Issue 11, pp.1286-1304
Managing Editor: Graham Pawelec
DOI: 10.52586/5024 Published: 30 November 2021
Open Access
Review

Circadian rhythms, cardiac arrhythmias and sudden death

Lourdes Vicent, Manuel Martínez-Sellés
Frontiers in Bioscience-Landmark Volume 26 Issue 11, pp.1305-1311
Managing Editor: Graham Pawelec
DOI: 10.52586/5025 Published: 30 November 2021
Open Access
Review

Nutrition, atherosclerosis, arterial imaging, cardiovascular risk stratification, and manifestations in COVID-19 framework: a narrative review

Smiksha Munjral, Puneet Ahluwalia, Ankush D. Jamthikar, Anudeep Puvvula, Luca Saba, Gavino Faa, Inder M Singh, Paramjit S. Chadha, Monika Turk, Amer M. Johri, Narendra N Khanna, Klaudija Viskovic, Sophie Mavrogeni, John R Laird, Gyan Pareek, Martin Miner, David W. Sobel, Antonella Balestrieri, Petros P Sfikakis, George Tsoulfas, Athanasios Protogerou, Prasanna Misra, Vikas Agarwal, George D. Kitas, Raghu Kolluri, Jagjit Teji, Mustafa Al-Maini, Surinder K. Dhanjil, Meyypan Sockalingam, Ajit Saxena, Aditya Sharma, Vijay Rathore, Mostafa Fatemi, Azra Alizad, Vijay Viswanathan, P K Krishnan, Tomaz Omerzu, Subbaram Naidu, Andrew Nicolaides, Jasjit S. Suri
Frontiers in Bioscience-Landmark Volume 26 Issue 11, pp.1312-1339
Managing Editor: Frontiers in Bioscience
DOI: 10.52586/5026 Published: 30 November 2021
Open Access
Review

Artificial intelligence in musculoskeletal conditions

Juan M. Román-Belmonte, Hortensia De la Corte-Rodríguez, Emérito Carlos Rodríguez-Merchán
Frontiers in Bioscience-Landmark Volume 26 Issue 11, pp.1340-1348
Managing Editor: Graham Pawelec
DOI: 10.52586/5027 Published: 30 November 2021
Open Access
Review

Protein kinases as therapeutic targets to develop anticancer drugs with natural alkaloids

Hanlin Ye, Linlin Wang, Li Ma, Maksim Ionov, Gan Qiao, Jianlin Huang, Li Cheng, Yuxi Zhang, Xiaohui Yang, Shousong Cao, Xiukun Lin
Frontiers in Bioscience-Landmark Volume 26 Issue 11, pp.1349-1361
Managing Editor: Graham Pawelec
DOI: 10.52586/5028 Published: 30 November 2021
Open Access
Mini-Review

The potentials of short fragments of human anti-microbial peptide LL-37 as a novel therapeutic modality for diseases

Keqiang Chen, Wanghua Gong, Jiaqiang Huang, Teizo Yoshimura, Ji Ming Wang
Frontiers in Bioscience-Landmark Volume 26 Issue 11, pp.1362-1372
Managing Editor: Graham Pawelec
DOI: 10.52586/5029 Published: 30 November 2021
Open Access
Conference/Metting Abstract

4th Summer School in Immuno-Oncology, July 1st–3rd, 2021, Athens, Greece

Ioannis V. Kostopoulos, Nikolaos Orologas-Stavrou, Nikolaos Angelis, Ioannis S. Pateras, Athanasios Kotsakis, Vassilis Georgoulias, Constantin N. Baxevanis, Graham Pawelec, Ourania E. Tsitsilonis
Frontiers in Bioscience-Landmark Volume 26 Issue 11, pp.1373-1382
Managing Editor: Frontiers in Bioscience
DOI: 10.52586/5030 Published: 30 November 2021